How do B-lymphocytes and T-lymphocytes recognize specific antigens?
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- B cell antigen receptors and antibodies bind to intact antigensin the blood and lymph. For antibodies, they can bind to antigens on the surface of pathogens or free in body fluids.
- T cell receptor binding to MHC-antigencomplex. T cell receptors recognise foreign antigens, then convey the message to the nucleus to induce a response. ... The antigensthat TCRs bind are small peptide fragments, or epitopes, displayed by MHC molecules on the surface of cells.
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B-cells have B-cell Receptors on their surfaces that can recognize million different types of antigens. ... T-cells too have T-cell receptors that detect the antigen on the surface of the Antigen Presenting cells. The antigens are presented to the T-cells through a MHC-Antigen complex
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