Question

how do chromatin fibre from chromosome

Answer 1

Chromatin fibre is same as chromosomes but the difference is, chromatin fibres arrange themselves in to chromosomes when the cell is just about to divide.

Hope it helps!

Answer 2

Core histone proteins package segments of this DNA molecule into nucleosomes, and linker histones further compact the resulting 'string of beads' into a 30‐nm chromatin fibre. In mitotic chromosomes, scaffold proteins fold the chromatin fibre into loops along its length.