how do proto-oncogenes and tumour suppressor genes normally regulate the cell cycle
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Proto-oncogenes positively regulate the cell.
- They influence the cell cycle beneficially. Proto-oncogenes can naturally become oncogenes as a direct result of specific mutations, disrupting normal cell division and causing cancer.
- Some mutations prohibit the cell from reproducing, preventing the mutations from being moved on to emerging generations.
- Tumor suppressor gene type for proteins limits cellular growth and encourages systematic cell death, in contrast to cellular proliferation-stimulating action of proto-oncogenes that propel the cell cycle forward.
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