How does non-stirred tank bioreactor affects the productivity of pharmaceutical product in compare of stirred bioreactor
Answers
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Answer:
Airlift bioreactors (ALBs) offer advantages over conventional systems, such as simplicity of construction, reduced risk of contamination, and efficient gas-liquid dispersion with low power consumption. ALBs are usually operated under atmospheric pressure.
In general, the stirred tank bioreactor has several advantages for the cultivation of shear-sensitive cells: existing industrial capacity, proven performance, ease of maintaining homogeneous conditions, and ease of scale-up and control.
1. There is increased surface area for oxygen transfer in the Sparged Stirred bio reactor, whereas there is less surface area as compared to Sparged tank for oxygen area in Simple Stirred bio reactors.
2. Bubbles increase the oxygen transfer area in Sparged whereas there is absence of oxygen bubbles in Simple stirred.