How electrophoresis can help to study Protein-DNA interaction under stress conditions
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• since DNA fragments are negatively charged molecules so they can be seperated by forcing them to move towards positive electrode under an electric field through a MEDIUM or MATRIX
• the most commonly used matrix is AGROSE GEL which is a natural polymer extracted from sea weeds ( red algae )
• DNA fragments seperate according to their size through sieving effect provided by the AGROSE GEL
This is how electrophoresis helps in studying Protein-DNA interaction .
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