How is a continuous culture system maintained in bioreactors and why?
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Continuous culture provides a higher degree of control than a batch culture. Growth rates can be regulated and maintained for extended periods. By varying the dilution rate, biomass concentration can be controlled. Secondary metabolite production can be sustained simultaneously along with growth
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In a continuous culture system, the used medium is drained out from one side while the fresh medium is added from the other to maintain the cells in their physiologically most active log/exponential phase. The continuous culture method produces larger biomass leading to a higher yield of the desired protein.
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