Question

How pCO2 is the factor which can interfere with the binding of oxygen with haemoglobin.
And in the case of binding of CO2 with haemoglobin pO2 is a major factor which could affect this binding? Explain.

Answer 1

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The binding depends on the partial pressure of ${CO_2}$ and ${O_2}$.

When ${pCO_2}$ is high, more binding of carbon dioxide occurs and when the ${pO_2}$ is high, more binding of oxygen occurs.

Answer 2

Answer:

pCO2 is major factor at tissue level and pO2 is major factor at alveolar level.

Explanation:

higer the partial pressure of particular gas more is the role of that gas in binding of other gases also.