How to use retinoids for treating excess sebum secretion?
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Abstract
One of the most common dermatologic concerns is oily skin, and the demand for effective treatment options is ever apparent. This review article addresses numerous topical treatment options such as retinoids, olumacostat glasaretil, and various cosmeceutical agents. several systemic and procedural techniques that incorporate isotretinoin, spironolactone, oral contraceptives, botulinum toxin, photodynamic therapy, and lasers are reviewed as well. Each treatment option is analyzed in terms of the proposed mechanism of action, efficacy reported in the literature, and potential adverse effects.
Keywords: Oily skin, seborrhea, sebum production, topical retinoids, olumacostat glasaretil, niacinamide, green tea, L-carnitine, isotretinoin, spironolactone, oral contraceptives, botulinum toxin, photodynamic therapy, diode laser
OILY SKIN IS A COMMON DERMATOLOGIC concern reported by all types of patients, including those without acne, given its association with larger facial pores and an “unclean” or “greasy” appearance (Figure 1). Even a quick search on Amazon.com for “oily skin treatment” reveals 9,907 products geared toward treating this very issue. Price ranges for these products vary from just a few dollars to nearly $1,000 each. One product on the high end of the price spectrum claims to be an “anti-aging fluid that combines modern technology with traditional knowledge of healing ingredients for oily or acne-prone skin.” Regardless of whether consumers believe these statements, this scenario sheds light on the demand for an effective treatment for oily skin.