How use of alcohol
and cocaine effect
blood pressure ?
Answers
Explanation:
Cocaine is a potent stimulant drug. It creates a variety of effects on the body. For example, it stimulates the central nervous system, causing a euphoric high. It also causes blood pressure and heart rate to increase, and it disrupts the heart’s electrical signals.
These effects to the heart and cardiovascular system increase a person’s risk for heart-related health issues, including a heart attack. Indeed, Australian researchers first used the phrase “the perfect heart-attack drug” in research they presented to the American Heart Association’s Scientific Sessions in 2012.
The risks to your heart and cardiovascular system don’t only come after years of cocaine use; the effects of cocaine are so immediate on your body that you could experience a heart attack with your first dose.
Answer:
Explanation:
Twenty regular cocaine users and 20 control subjects were recruited by word-of-mouth. Cardiovascular magnetic resonance was performed to assess cardiac and vascular structure and function. Cocaine users had higher systolic blood pressure compared to non-users (134±11 vs 126±11 mmHg, p = 0.036), a finding independent of age, body surface area, smoking and alcohol consumption. Cocaine use was associated with increased arterial stiffness - reflected by reduced aortic compliance (1.3±0.2 vs 1.7±0.5 cm2×10−2.mmHg−1, p = 0.004), decreased distensibility (3.8±0.9 vs 5.1±1.4 mmHg−1.10−3, p = 0.001), increased stiffness index (2.6±0.6 vs 2.1±0.6, p = 0.005), and higher pulse wave velocity (5.1±0.6 vs 4.4±0.6 m.s−1, p = 0.001). This change in aortic stiffness was independent of vessel wall thickness. Left ventricular mass was 18% higher in cocaine users (124±25 vs 105±16 g, p = 0.01), a finding that was independent of body surface area, and left atrial diameter was larger in the user group than controls (3.8±0.6 vs 3.5±0.3 cm, p = 0.04). The increased left ventricular mass, systolic blood pressure and vascular stiffness measures were all associated with duration and/or frequency of cocaine use. No late gadolinium enhancement or segmental wall motion abnormalities were seen in any of the subjects.