how viruses can be destroyed
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Explanation:
• Virus titers are calculated from the plaque counts and dilutions. The virus titer sof macrophages lower than corresponding thermal inactivation controls suggest virus clearance from the macrophage or prolonged eclipse phase of virus in the macrophage.
• Slope of curve can be used to determine the rate of clearance. The number of plaques gives the number of infectious centers, that is, the number of macrophages containing infectious or potentially infectious virus.
• Extrinsic antiviral activity, the ability of certain mononuclear phagocytes to reduce virus growth in infected susceptible host cells on mixed culture, is another means by which macrophages may assist in host defense against viruses.
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