How will you prepare propan 1 amine form an alkyl halide and a nitrile compound and 1 nitropropane
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We use two reactions to prepare propan-1-amine .
First we convert butane nitrile to butanamide by partial hydrolysis of butane nitrile.
CH3–CH2-CH2-CN ————— > CH3-CH2-CH2-CONH2.
This reaction is carried in presence of HCl at 40 degrees centigrade.
Then we convert the butanamide to propan-1-amine by Hoffmann bromamide degradation
CH3–CH2-CH2-CONH2 + Br2+4 NaOH →
CH3–CH2-CH2-NH2 + 2Na2CO3+2NaBr+2H2O.
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First we convert butane nitrile to butanamide by partial hydrolysis of butane nitrile.
CH3–CH2-CH2-CN ————— > CH3-CH2-CH2-CONH2.
This reaction is carried in presence of HCl at 40 degrees centigrade.
Then we convert the butanamide to propan-1-amine by Hoffmann bromamide degradation
CH3–CH2-CH2-CONH2 + Br2+4 NaOH →
CH3–CH2-CH2-NH2 + 2Na2CO3+2NaBr+2H2O.
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