Question

If blood group AB is the universal receipient and it has both the antigens then if we mix blood group A with blood group AB and blood group A has antibody B then why not anti-B in blood group AB attacks antigen B in blood group A ?
If blood group O is the universal donor and it has both the antibodied then if we mix blood group O with blood group A and blood group A has antigen A then why not anti-A in blood group O attacksl antigen A in blood group A ?

Answer 1

Hey..!!!!

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The different blood types refer to the different types of antigens on the surface of our red blood cells. There are 3 main ones: A, B, and D. A and B determine the type of blood you have (A, B, AB, or O type) and D determines whether your blood is positive or negative- the presence of the D antigen (also known as the Rh factor mentioned in another comment) means you are positive. For example, having the antigens A and D make your blood A+. I
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f you have A and B but no D, your blood is AB-. Having only the D antigen without A or B means you have O+ blood, and a lack of all 3 antigens means you have O- blood.
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The reason this is a problem during blood transfusions is because if you have a certain antigen, it means you have an antibody for the other antigens you dont have. For example, if you have type A+ blood, meaning you have the A and D antigens, you have a B antibody.
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If your A+ blood were to come into contact with a B type blood, the B antibodies in your blood would react with the B antigens in the B blood, causing the B blood to coagulate and virtually be unusable.
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This is why type O- is the "universal donor", because it has no antigens for anybody else's antibodies to react with. This is also why AB+ is the "universal acceptor" because it has no antibodies to coagulate any type of donor blood.

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I Hope it's help you...!!!!

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Answer 2

Answer: person with o blood group is considered as universal donor thought it has antibodies against antigens A and B.

Explanation:this i would like to explain in just two points :

1. The whole blood is not transfused, the amount of donor's blood is less as compared to the patient's whole amount of blood... Antibodies may react but the rxn is very small that it does not cause any severe pblm.

2. Mostly blood or plasma cellsare centrifuged before transfusion so that erythrocytes without antibodies can be transfused....

Hope this will be helpful..... Thank you :)