Question

ii) Impurities in pharmaceutical preparation may be due to following sources:
(a) Raw material
(b) Manufacturing process
(c) Chemical instability
(d) All of these​

Answer 1

Answer:

d

Explanation:

1

raw material coming from various sources may have impurities and is not properly filtered

2

during manufacturing process the machinery may be faulty

3

preparations require expertise and constant monitoring of the required proportions and ratios. any deviation can lead to imbalance

Answer 2

Impurities in pharmaceutical preparation may be due to raw materials, manufacturing process as well as chemical unstability. (Option d)

A list of impurities expected to be present in a pharmaceutical item may be generated based on knowledge about the raw materials used, the production process, and the finished product's stability. Impurities can also be caused by physical contamination and poor storage conditions.

The following are the causes of contaminants in medicinal substances:

1. Raw Materials Used in Pharmaceutical Substance Production:

Pharmaceutical compounds are taken from natural sources or created from chemical precursors.  Pharmaceutical compounds are extracted from natural sources or manufactured from chemical precursors. Because rock salt contains small quantities of calcium and magnesium chlorides, sodium chloride generated from it will have a small amount of these chemical impurities.

2. Manufacturing Process

The manufacturing process or method may introduce additional contaminants into the final product by contamination by reagents, catalysts, and solvents used at various stages of the production process.

(A) Manufacturing reagents (B) Regents used to remove other impurities (C) Solvents (D) Reaction containers (E) Intermediates (F) Atmospheric pollution during the manufacturing process (G) Manufacturing risks.