In a cell rich in malonate, the Krebs cycle will not produce
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As the enzymes of the Krebs cycle oxidize fuel molecules to carbon dioxide, the coenzymes NAD + , FAD, and coenzyme Q (also known as ubiquinone) are reduced. In order for the cycle to continue, these reduced coenzymes must become reoxidized by transferring their electrons to oxygen, thus producing water.
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Citrate Provides a Bridge Between Carbohydrate and Fatty Acid Metabolism. Citrate is produced in the Krebs cycle (also known as the citric acid cycle or TCA cycle) from the aldol condensation of oxaloacetate, the end product of a previous turn of the cycle, and acetyl-CoA (Figure 1) (36).Feb 5,
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