Question

In metazoan cell cycle, metaphase to anaphase transition is regulated by the activity of

Answer 1

is regulated by sister chromatids

Answer 2

ANSWER:

In metazoan cell cycle, the transition from metaphase to anaphase is regulated by the activity of sister chromatids.  

EXPLANATION:

Sister chromatids are identical copies formed by the DNA replication of chromosomes. In other words, the copies belong to the same chromosome and are joined by common centromere.

These are considered to be crucial to the process of cell replication and also cell division. The "separation of sister chromatids" is what regulates the cell division and transition from metaphase to anaphase