In which part of the nephron esidrix drug performs its action as a diuretic agent to manage the high blood pressure?
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Mechanism of action
Hydrochlorothiazide belongs to thiazide class of diuretics. It reduces blood volume by acting on the kidneys to reduce sodium (Na+) reabsorption in the distal convoluted tubule.
License data: EU EMA: by INN; US DailyMed: Hydrochlorothiazide
Excretion: Primarily kidney (>95% as unchanged drug)
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