Biology, asked by Areeba1907, 1 year ago

Inhibitors of dna replication

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Answered by Somyasisodiya

We describe a novel 25 kDa protein, geminin, whichinhibits DNA replication and is degraded during the mitotic phase of the cell cycle. Geminin has a destruction box sequence and is ubiquitinated anaphase-promoting complex (APC) in vitro. In synchronized HeLa …

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