Integrons and it's various types ,role of integrons in microbial drug resistance
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integrons have been isolated from Serratia marcescens, Klebsiella pneumonia, Delftia spp., E. coli, Acinetobacter spp., Pseudomonas aeruginosa, Pseudomonas putida, Citrobacter freundii, Alcaligenes xylosoxidans and Salmonella spp. 3,18 . Only some studies have analyzed the frequency of occurrence of integrons, and the association between integron carriage and antimicrobial susceptibility in Iran. ...
... The first class 3 integron was discovered in the Serratia marcescens isolated from patient with UTI in Japan in 1993 and the second report in Klebsiella pneumoniae 18 31 reported that class 3 integrase, sharing 60% amino acid identity with the class 1 integrase and carried the gene coding for resistance to beta-lactams. In this study, a significant relationship was found between class 3 integron and resistance to kanamycin, streptomycin, tetracycline, gentamicin, ampicillin and Trimethoprim-sulfamethoxazole. ...
... The first class 3 integron was discovered in the Serratia marcescens isolated from patient with UTI in Japan in 1993 and the second report in Klebsiella pneumoniae 18 31 reported that class 3 integrase, sharing 60% amino acid identity with the class 1 integrase and carried the gene coding for resistance to beta-lactams. In this study, a significant relationship was found between class 3 integron and resistance to kanamycin, streptomycin, tetracycline, gentamicin, ampicillin and Trimethoprim-sulfamethoxazole. ...
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