Is breast cancer inherited?
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Most cases of breast cancer are not caused by inherited genetic factors. These cancers are associated with somatic mutations in breast cells that are acquired during a person's lifetime, and they do not cluster in families. In hereditary breast cancer, the way that cancer risk is inherited depends on the gene involved.
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Breast cancer is a disease in which certain cells in the breast become abnormal and multiply uncontrollably to form a tumor. Although breast cancer is much more common in women, this form of cancer can also develop in men. In both women and men, the most common form of breast cancer begins in cells lining the
The nipple and areola are shown on the outside of the breast. The lymph nodes, lobes, lobules, ducts, and other parts of the inside of the breast are also shown.
Credit: Terese Winslow LLC/National Cancer Institute
Use of illustrations and other content
" data-alt="The nipple and areola are shown on the outside of the breast. The lymph nodes, lobes, lobules, ducts, and other parts of the inside of the breast are also shown." title="Image" data-source-href="https://visualsonline.cancer.gov/details.cfm?imageid=7127" class="img-popup img-popup-2" target="_blank" href="https://ghr.nlm.nih.gov/art/large/female-breast-anatomy.jpeg" data-toggle="lightbox" style="box-sizing: border-box; background-color: transparent; color: rgb(85, 26, 139); text-decoration: none; border-bottom: 1px dashed rgb(144, 144, 144);">milk ducts (ductal cancer). In women, cancer can also develop in the glands that produce milk (lobular cancer). Most
Anatomy of the male breast showing the nipple, areola, fatty tissue, and ducts. Nearby lymph nodes, ribs, and muscle are also shown.
Credit: Terese Winslow LLC/National Cancer Institute
Use of illustrations and other content
" data-alt="Anatomy of the male breast showing the nipple, areola, fatty tissue, and ducts. Nearby lymph nodes, ribs, and muscle are also shown." title="Image" data-source-href="https://visualsonline.cancer.gov/details.cfm?imageid=9206" class="img-popup img-popup-2" target="_blank" href="https://ghr.nlm.nih.gov/art/large/male-breast-anatomy.jpeg" data-toggle="lightbox" style="box-sizing: border-box; background-color: transparent; color: rgb(85, 26, 139); text-decoration: none; border-bottom: 1px dashed rgb(144, 144, 144);">men have little or no lobular tissue, so lobular cancer in men is very rare.
In its early stages, breast cancer usually does not cause pain and may exhibit no noticeable symptoms. As the cancer progresses, signs and symptoms can include a lump or thickening in or near the breast; a change in the size or shape of the breast; nipple discharge, tenderness, or retraction (turning inward); and skin irritation, dimpling, or scaliness. However, these changes can occur as part of many different conditions. Having one or more of these symptoms does not mean that a person definitely has breast cancer.
The nipple and areola are shown on the outside of the breast. The lymph nodes, lobes, lobules, ducts, and other parts of the inside of the breast are also shown.
Credit: Terese Winslow LLC/National Cancer Institute
Use of illustrations and other content
" data-alt="The nipple and areola are shown on the outside of the breast. The lymph nodes, lobes, lobules, ducts, and other parts of the inside of the breast are also shown." title="Image" data-source-href="https://visualsonline.cancer.gov/details.cfm?imageid=7127" class="img-popup img-popup-2" target="_blank" href="https://ghr.nlm.nih.gov/art/large/female-breast-anatomy.jpeg" data-toggle="lightbox" style="box-sizing: border-box; background-color: transparent; color: rgb(85, 26, 139); text-decoration: none; border-bottom: 1px dashed rgb(144, 144, 144);">milk ducts (ductal cancer). In women, cancer can also develop in the glands that produce milk (lobular cancer). Most
Anatomy of the male breast showing the nipple, areola, fatty tissue, and ducts. Nearby lymph nodes, ribs, and muscle are also shown.
Credit: Terese Winslow LLC/National Cancer Institute
Use of illustrations and other content
" data-alt="Anatomy of the male breast showing the nipple, areola, fatty tissue, and ducts. Nearby lymph nodes, ribs, and muscle are also shown." title="Image" data-source-href="https://visualsonline.cancer.gov/details.cfm?imageid=9206" class="img-popup img-popup-2" target="_blank" href="https://ghr.nlm.nih.gov/art/large/male-breast-anatomy.jpeg" data-toggle="lightbox" style="box-sizing: border-box; background-color: transparent; color: rgb(85, 26, 139); text-decoration: none; border-bottom: 1px dashed rgb(144, 144, 144);">men have little or no lobular tissue, so lobular cancer in men is very rare.
In its early stages, breast cancer usually does not cause pain and may exhibit no noticeable symptoms. As the cancer progresses, signs and symptoms can include a lump or thickening in or near the breast; a change in the size or shape of the breast; nipple discharge, tenderness, or retraction (turning inward); and skin irritation, dimpling, or scaliness. However, these changes can occur as part of many different conditions. Having one or more of these symptoms does not mean that a person definitely has breast cancer.
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