is erythropoietin only in bones?
Answers
Explanation:
Erythropoietin (/ɪˌrɪθroʊˈpɔɪ.ɪtɪn, -rə-, -pɔɪˈɛtɪn, -ˈiːtɪn/;[5][6][7] EPO), also known as haematopoietin or haemopoietin, is a glycoprotein cytokine secreted by the kidney in response to cellular hypoxia; it stimulates red blood cell production (erythropoiesis) in the bone marrow. Low levels of EPO (around 10 mU/mL) are constantly secreted sufficient to compensate for normal red blood cell turnover. Common causes of cellular hypoxia resulting in elevated levels of EPO (up to 10 000 mU/mL) include any anemia, and hypoxemia due to chronic lung disease.
Before birth RBC are first synthesized in the Yolk sac ...
After that RBC is synthesized in liver then in spleen .. And finally in the bone marrow ..
The lifespan of RBC is 120 days following which With The breakdown in spleen so it is also called the graveyard of RBC .
It is also called the blood bank because it is the reservoir of RBC ....