Karyotypes can be studied to determine an organism’s chromosomal makeup and to detect genetic defects. Down syndrome is a genetic disorder that is also called trisomy 21. What would trisomy 21 look like in a karyotype?
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Discuss the role of enzyme DNA ligase plays during DNA replication. ... However, it is discontinous at a lagging strand in the form of DNA segments. These DNA segments are known as Okazaki fragments. These fragments are later joined with the help of the enzymes DNA ligase. DNA base pairing, the base pairs are adenine-thymine and guanine-cytosine. ... If double stranded DNA has 14% G (guanine), what percent A (adenine), T (thymine) and C (cytosine) would you expect? ... If a sample of DNA has 15% Adenine, then what percentage of cytosine does it have?
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'Trisomy 21' is caused by meiotic nondisjunction event. A normal gamete has 'one copy' of each chromosome but when non disjunction occurs the gamete contains extra copy of chromosomes which results in this disorder.
Explanation:
A normal reproduction occurs when the egg cell has 23 chromosomes from mother and 23 chromosomes from father and a total of 46 chromosomes are present but in case of Down syndrome the error occurs.
The sperm cell keeps the two copy of number 21 chromosome instead of one. That extra copy is carried to 'every cell' in the body which also known as 'translocation down syndrome'.
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