Question

Lysosomes exibit polymorphism. Explain

Answer 1

Polymorphism, i.e. existence of a structure in more than one form, is an important feature of lysosomes. Several different forms of lysosomes have been identified within the cell as primary lysosomes, secondary lysosomes, residual bodies and autophagic vacuoles.

Primary lysosomes: These are newly formed organelles. They are believed to be derived from the maturing face of Golgi complex whose digestive enzymes have not yet taken part in hydrolysis.

Secondary lysosomes: are formed from fusion of primary lysosomes with the vesicles containing variety of substrates known as 'phagosome'. After fusion, their membrane undergoes a change and enzymes are activated so that the substrate is digested. After activation they may continue hydl-oiysis repeatedly.

Residual bodies: lncomplete digestion of foreign substances leads to the formation of residual bodies. Residual bodies are huge, irregular in shape and are electron dense.
Lysosomes are responsible for the .intracellular digestion of a variety of substances such as food molecules, disease causing organisms, etc. This process is called heterophagy.

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Answer 2

Polymorphism, i.e. existence of a structure in more than one form, is an important feature of lysosomes. Several different forms of lysosomes have been identified within the cell as primary lysosomes, secondary lysosomes, residual bodies and autophagic vacuoles.