Make a creative short story about the phases of cell cycle and its checkpoints. Highlight each function of the checkpoints and the characteristics of the different stages of the cycle
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Cell cycle checkpoints are surveillance mechanisms that monitor the order, integrity and fidelity of the major events of the cell cycle.
Explanation:
- These include growth to the appropriate cell size,replication and integrity of the chromosomes and their accurate segregation at mitosis.
- Different cell cycle checkpoints have evolved that prevent replication of damaged DNA and premature entry to or exit from mitosis and allow time for DNA repair after encountering DNA damage.
- The main cell cycle checkpoints are the G1/S checkpoint, the intra-S checkpoint and the G2/M checkpoint [60].
- The cell cycle of stage process in which the cell increases in size (gap 1 or G1, stage), copies its DNA (synthesis, or S, stage), prepares to divide (gap 2 or G2, stage) and divides (mitosis or M, stage).
- The stages G1, S, and G2 make up interphase which accounts for the span between cell divisions.
- In eukaryotes the cell cycle consists of four discrete phases: G1, S, G2, and M.
- The S or synthesis phase is when DNA replication occurs and the M or mitosis phase is when the cell actually divides.The other two phases G1 and G2 the so called gap phases are less dramatic but equally important.
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