Mechanism of 1 3 dipolar cycloaddition reaction with an example
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Huisgen Cycloaddition
1,3-Dipolar Cycloaddition
1,3-Dipolar Cycloaddition
The Huisgen Cycloaddition is the reaction of a dipolarophile with a 1,3-dipolar compound that leads to 5-membered (hetero)cycles. Examples of dipolarophiles are alkenes and alkynes and molecules that possess related heteroatom functional groups (such as carbonyls and nitriles). 1,3-Dipolar compounds contain one or more heteroatoms and can be described as having at least one mesomeric structure that represents a charged dipole.
Examples of linear, propargyl-allenyl-type dipoles
An example of an allyl-type dipole. See: Ozonolysis
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