Question

MECHANISM of carbylamine reaction. Don't give the equation of reaction i WANT MECHANISM.

Answer 1

Primary amines on heating with chloroform in presence of alcoholic potassium hydroxide solution,result in the formation of alkaneisonitrile,which has characteristic offensive odour.The reaction is known as carbylamine reaction or isocyanide reaction.The mechanism begins with the formation of the electrophile followed by the attack of dichlorocarbene(electrophile)on nucleophilic nitrogen of primary amine,eventually removal of HCl(2moles)get eliminated leading to the formation of isonitrile.