mechanism of reimer tiemann reaction
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mechanism of reimer tiemann reaction
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it is an chemical reaction used for the ortho-formylation of phenols
MECHANISM
In this reaction the Generation of chloroform carbanion by deprotonation of chloroform with a strong base.
This chloroform carbanion generated, quickly undergoes alpha elimination to yield dichlorocarbene.
phenol atom also undergoes deprotonation in the presence of a strong base like KOH to yield a negatively charged phenoxide ion.
it will increases the nucleophilicity of phenoxide ion.
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