meosis action on how do organisims reproduce lesson
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Phases of meiosisIn many ways, meiosis is a lot like mitosis. The cell goes through similar stages and uses similar strategies to organize and separate chromosomes. In meiosis, however, the cell has a more complex task. It still needs to separate sister chromatids (the two halves of a duplicated chromosome), as in mitosis. But it must also separate homologous chromosomes, the similar but nonidentical chromosome pairs an organism receives from its two parents.These goals are accomplished in meiosis using a two-step division process. Homologue pairs separate during a first round of cell division, called meiosis I. Sister chromatids separate during a second round, called meiosis II.Since cell division occurs twice during meiosis, one starting cell can produce four gametes (eggs or sperm). In each round of division, cells go through four stages: prophase, metaphase, anaphase, and telophase.Meiosis IBefore entering meiosis I, a cell must first go through interphase. As in mitosis, the cell grows during G_11 start subscript, 1, end subscript phase, copies all of its chromosomes during S phase, and prepares for division during G_22 start subscript, 2, end subscript phase.During prophase I, differences from mitosis begin to appear. As in mitosis, the chromosomes begin to condense, but in meiosis I, they also pair up. Each chromosome carefully aligns with its homologue partner so that the two match up at corresponding positions along their full length.For instance, in the image below, the letters A, B, and C represent genes found at particular spots on the chromosome, with capital and lowercase letters for different forms, or alleles, of each gene. The DNA is broken at the same spot on each homologue—here, between genes B and C—and reconnected in a criss-cross pattern so that the homologues exchange part of their DNA.Image of crossing over. Two homologous chromosomes carry different versions of three genes. One has the A, B, and C versions, while the other has the a, b, and c versions. A crossover event in which two chromatids—one from each homologue—exchange fragments swaps the C and c genes. Now, each homologue has two dissimilar chromatids.One has A, B, C on one chromatid and A, B, c on the other chromatid.The other homologue has a, b, c on one chromatid and a, b, C on the other chromatid.This process, in which homologous chromosomes trade parts, is called crossing over. It's helped along by a protein structure called the synaptonemal complex that holds the homologues together. The chromosomes would actually be positioned one on top of the other—as in the image below—throughout crossing over; they're only shown side-by-side in the image above so that it's easier to see the exchange of genetic material.Image of two homologous chromosomes, positioned one on top of the other and held together by the synaptonemal complex.Image credit: based on "The process of meiosis: Figure 1" by OpenStax College, Biology, CC-BY 3.0You can see crossovers under a microscope as chiasmata, cross-shaped structures where homologues are linked together. Chiasmata keep the homologues connected to each other after the synaptonemal complex breaks down, so each homologous pair needs at least one. It's common for multiple crossovers (up to 252525!) to take place for each homologue pair ^11start superscript, 1, end superscript.The spots where crossovers happen are more or less random, leading to the formation of new, "remixed" chromosomes with unique combinations of alleles.After crossing over, the spindle begins to capture chromosomes and move them towards the centre of the cell (metaphase plate). This may seem familiar from mitosis, but there is a twist. Each chromosome attaches to microtubules from just one pole of the spindle, and the two homologues of a pair bind to microtubules from opposite poles. So, during metaphase, I, homologue pairs—not individual chromosomes—line up at the metaphase plate for separation.The phases of meiosis I.Prophase I: The starting cell is diploid, 2n = 4. Homologous chromosomes pair up and exchange fragments in the process of crossing over.Metaphase I: Homologue pairs line up at the metaphase plate.Anaphase I: Homologues separate to opposite ends of the cell. Sister chromatids stay together.Telophase I: Newly forming cells are haploid, n = 2. Each chromosome still has two sister chromatids, but the chromatids of each chromosome are no longer identical to each other.When the homologous pairs line up at the metaphase plate, the orientation of each pair is random. For instance, in the diagram above, the pink version of the big chromosome and the purple version of the little chromosome happen to be positioned towards the same pole and go into the same cell. But the orientation could have equally well been flipped, so that both purple chromosomes went into the cell together. This allows for the formation of gametes with different sets of homologu
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