Question

monocyte derived macrophages conversion in pig in how many days

Answer 1

Typhimurium crosses the intestinal epithelial barrier and comes into contact with cells of the host immune system. Mononuclear phagocytes which comprise macrophages and dendritic cells (DC) are of key importance for the outcome of Salmonella infection. Although macrophages and DC may differentiate from a common precursor, their capacities to process and present antigen differ significantly. In this study, we therefore compared the response of porcine macrophages and DC differentiated from peripheral blood monocytes to S. Typhimurium and one of the most potent bacterial pathogen associated molecular patterns, bacterial lipopolysaccharide. To avoid any bias, the expression was determined by protein LC-MS/MS and

Answer 2

The life span of a circulating monocyte is fairly brief and most undergo apoptosis after about 24 h. Some monocytes do, however, migrate into tissues or to the sites of damage or infection where they subsequently mature into macrophages.

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