Monogenetic disorder write Note
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Monogenic Disorders (Single Abnormal Gene) These disorders are the result of a single defective gene on the autosomes. They are inherited according to Mendel's Laws (Mendelian disorders). The mutation can be spontaneous and where there is no previous family history.
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Monogenic disorders are Mendelian disorders for which changes in a single gene are implicated in the disease process and that usually exhibit characteristic inheritance patterns (ie, additive, dominant, or recessive genetic models).
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