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Arranging the structure
a) Br 1
I
2 C2H5- C-H 4
I
CH3 3
By moving according to priority order we are moving in anti-clock wise and lowest priority one in horizontal plane. So it will be R designation
b) CH3 3
I
2 CH2OH-C - H 4
I
COOH 1
By moving according to priority order we are moving in clockwise and lowest priority one in horizontal plane.
So it will be S designation.
(P.S - priority order chart you can get from any standard source)
hope this will help you
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