Number of ATP molecules spent to convert ammonia to urea is
a) four
b) two
c) three
d) one
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Ammonia gets converted to urea in the hepatocytes of liver in five steps. This is known as the urea cycle.
The first two steps takes place in the mitochondria and the last three steps in cytosol. The urea travels through blood onto the kidney and gets excreted by urine.
This cycle was first discovered by Hans Krebs and his student Kurt Henseleit in the year 1932. If we consider only the urea cycle, and not the other bio-pathways that are linked, for producing one urea molecule at least 4 ATP molecules are used. Thus the answer is “A”.
The first two steps takes place in the mitochondria and the last three steps in cytosol. The urea travels through blood onto the kidney and gets excreted by urine.
This cycle was first discovered by Hans Krebs and his student Kurt Henseleit in the year 1932. If we consider only the urea cycle, and not the other bio-pathways that are linked, for producing one urea molecule at least 4 ATP molecules are used. Thus the answer is “A”.
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