Question

Phenylketonuria is caused by defect in what metabolism?

Answer 1

phenylketonuria is an inherited condition caused by a defect in the PAH gene. The PAH gene helps create phenylalanine hydroxylase, the enzyme responsible for breaking down phenylalanine. A dangerous buildup of phenylalanine can occur when someone eats high-protein foods, such as eggs and meat.

Answer 2

Explanation:

Phenylketonuria is a autosomal mendelian disorder .

It is due to recessive gene on chromosome No - 12 .

It accumulate in nerve cells of brain and hence lead to the mental retardation