prepare and submit acetanilide from analine
Answers
Explanation:
Acetanilide is prepared from aniline when it reacts with acetic anhydride/glacial acetic acid in the presence of zinc dust. A mixture of aniline, glacial acetic acid, acetic anhydride and zinc dust is refluxed under anhydrous condition and then poured the mixture into ice cold water to get acetic anhydride precipitate. The crude precipitate of acetic anhydride is recrystallized to get pure crystals of acetanilide.
Zinc is used to prevent the oxidation of aniline during the chemical reaction. Acetanilide is medicinally important and it is used as febrifuge.
Acetanilide cal also be prepared by acetylating aniline with acetic anhydride in the presence of concentrated hydrochloric acid. Dissolve aniline in hydrochloric acid and add acetic anhydride stir well. Pour the mixture to sodium acetate in water. Acetanilide is formed which can be separated and recrystallised by ethyl alcohol.
Other names – N-phenylacetamide, N-phenylethanamide, Acetanil