Primary stress of spleen
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Acute anemic stress induces a physiological response that includes the rapid development of new erythrocytes. This process is referred to as stress erythropoiesis, which is distinct from steady state erythropoiesis. Much of what we know about stress erythropoiesis comes from the analysis of murine models. In this review, we will discuss our current understanding of the mechanisms that regulate stress erythropoiesis in mice and discuss outstanding questions in the field.
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Explanation:
The spleen is a significant organ of the hematologic and reticuloendothelial systems. It is an intraperitoneal organ located in the left upper quadrant of the abdomen posterior and lateral to the stomach.The spleen is situated anatomically behind the 9 and 11 ribs on the left side of the body.
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