Question

Product water and hemodialysis solution preperation

Answer 1

Compositions comprising: (1) an acid-containing highly concentrated calcium salt solution which optionally can also contain magnesium ions and minor amounts of other physiologically acceptable metal ions; and (2) a particulate admixture comprising sodium bicarbonate, sodium chloride and, optionally, potassium chloride, dextrose and other physiologically acceptable materials which, in aqueous solution, are unreactive to sodium bicarbonate. Also presented is a method for preparing a dialysate comprising: (1) preparing a concentrated sodium bicarbonate solution by dissolving a particulate admixture comprising sodium bicarbonate, sodium chloride and, optionally, potassium chloride, dextrose and other physiologically acceptable materials unreactive to sodium bicarbonate in the presence of water; (2) preferably separately diluting: (a) an acid-containing highly concentrated calcium salt solution which optionally can also contain magnesium ions and minor amounts of other physiologically acceptable metal ions, and (b) the concentrated sodium bicarbonate solution; and (3) admixing the two resulting diluted solutions to form the dialysate