Q.13 Nifedipine is the derivative of
1,5-dihydro pyrimidine
ОО
1,3-dihydro pyrazine
1,4-dihydro pyridine
1,4-dihydro piperidine
Answers
Answer:
Structure
Nifedipine_small.png
Nifedipine_3D_Structure.png
Nifedipine_Crystal_Structure.png
Find Similar Structures
Chemical Safety
Irritant Health Hazard
Laboratory Chemical Safety Summary (LCSS) Datasheet
Molecular Formula
C17H18N2O6
Synonyms
nifedipine
21829-25-4
Adalat
Procardia
Procardia XL
More...
Molecular Weight
346.3 g/mol
Dates
Modify
2021-01-02
Create
2004-09-16
Description
Nifedipine is a dihydropyridine calcium channel blocking agent. Nifedipine inhibits the transmembrane influx of extracellular calcium ions into myocardial and vascular smooth muscle cells, causing dilatation of the main coronary and systemic arteries and decreasing myocardial contractility. This agent also inhibits the drug efflux pump P-glycoprotein which is overexpressed in some multi-drug resistant tumors and may improve the efficacy of some antineoplastic agents. (NCI04)