Question

Q) Briefly mention the mechanism of action of FSH ?

==> long answer, explain briefly !!
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Answer 1

$\huge\star\underline\bold\red{Follicle\:stimulating \:hormone}$

• Follicle stimulating hormone is produced by the pituitary gland. It regulates the functions of both the ovaries and testes.
• Lack or insufficiency cause infertility or subfertility both in men and women.

$\small\star\underline\bold\blue{Function-}$

• In women, this hormone stimulates the growth of ovarian follicles in the ovary before the release of an egg from one follicle at ovulation. It also increases oestradiol production.
• In men, follicle stimulating hormone acts on the Sertoli cells of the testes to stimulate sperm production (spermatogenesis).

$\small\star\underline\bold\blue{What \:happens\: if \:I \:have \:too \:much \:follicle\: stimulating\: hormone?}$

• Most often, raised levels of follicle stimulating hormone are a sign of malfunction in the ovary or testis.
• If the gonads fail to create enough oestrogen, testosterone and/or inhibin, the correct feedback control of follicle stimulating hormone production from the pituitary gland is lost and the levels of both follicle stimulating hormone and luteinising hormone will rise.
• This condition is called hypergonadotrophic-hypogonadism.

$\small\star\underline\bold\blue{What \:happens\: if \:I \:have \:too \:less \:follicle\: stimulating\: hormone?}$

• In women, a lack of follicle stimulating hormone leads to incomplete development at puberty and poor ovarian function (ovarian failure).
• In this situation ovarian follicles do not grow properly and do not release an egg, thus leading to infertility.
• Since levels of follicle stimulating hormone in the bloodstream are low, this condition is called hypogonadotrophic-hypogonadism.

$\small\star\underline\bold\blue{Alternative \:names-}$

FSH; follitropin (pharmaceutical preparations)

Answer 2

Answer:

Follicle-stimulating hormone (FSH) is a hormone which synthesized and secreted by the gonadotropic cells of the anterior pituitary gland, it regulates the development, growth, and reproductive processes of the human body. FSH shows its effect by binding to its specific receptors present on the ovarian cell membrane. Binding of FSH to its specific receptor present over the cell surface activates an enzyme called adenylate cyclase. This enzyme converts ATP into cyclicAMP. The cyclicAMP is called the second messenger and carries out various biochemical responses in the cell by activating the existing enzyme system in the cell. The biochemical responses then lead to physiological responses like ovarian growth.

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