Question

Q2 Read the following and answer the questions from 2() to 2(W) given
below:
Sickle cell anemia is a genetic disorder where the body produces an abnormal
hemoglobin called hemoglobin S. Red blood cells are normally flexible and
round, but when the hemoglobin is defective, blood cells take on a "sickle or
crescent shape. Sickle cell anemia is caused by mutations in a gene called HBB
It is an inherited blood disorder that occurs Il both the maternal and paternal
copies of the HBB gene are defective. In other words, if an individual receives
Scanned with
Just one copy of the defective HBB gene, either from mother or father, then the
Individual has no sickle cell anemia but has what is called 'sickle cell trait".
People with sickle cell trait usually do not have any symptoms or problems but
they can pass the mutated gene onto their children. There are three inheritance
scenarios that can lead to a child having sickle cell anemia:
Both parents have sickle cell trait
One parent has sickle cell anemia and the other has sickle cell trait
- Both parents have sickle cell anemia
I. Sickle cell anomia is al an
disease.
a X linked
b. autosomal dominant
c. autosomal recessive
d. Y linked
IL. If both parents have sickle cell tralt, then there is
of the child
having sickle cell anemia.
a 25 % risk
b. 50 % risk
C, 75% risk
d. No risk
IU. If both parents have sickle cell tralt, then there is
of the child
having sickle cell tralt.
a. 2% risk
b. 50 % risk
15% risk
d. No risk
1. If ono parent hag sickle cell anemia and the other has sickle cell tralt, there is
that their children will have sickle cell anemia and
will
havo sickle cell tralt.
a. 25 % risk, 76% risk
b. 50 % risk, 50% risk
c. 75% risk, 25% risk
d. No risk
V.
10
1233
2318
2200
00
1998 1999 2000 2001 2002 2003 2004 2005
Yea
No patients win SCD QNo. of two
The following statements are drawn as conclusions from the above data (Kenya).
L. Patients with SCD (Sickle Cell Disease) are less likely to be infected with
malaria
Il Patients with SCD (Sickle Cell Disease) are more likely to be infected
with malaria.
1. Over the years the percentage of people infected with malaria has been
decreasing
IV. Year 2000 saw the largest percentage difference between malaria patients
with and without SCD.
Choose from below the correct alternative.
a. only I is true
b. I and IV are true
c. UI and II are true
d. I and III are true​

Answer 1

Answer:

1. (c) autosomal recessive

2. (a) 25%

3. (b) 50%

4.(b) 50% risk, 50% risk

5.(d) l and lll are true