Question

Question 7: What is urea cycle? explain the molecular mechanism of electrolyte reabsorption at different locations of medullary nephron.
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Answer 1

Answer:

The urea cycle is a cycle of biochemical reactions that produces urea (NH₂)₂CO from ammonia. This cycle occurs in ureotelic organisms. The urea cycle converts highly toxic ammonia to urea for excretion. This cycle was the first metabolic cycle to be discovered, five years before the discovery of the TCA cycle

Sodium passes along an electrochemical gradient (passive transport) from the lumen into the tubular cell, together with water and chloride which also diffuse passively. Water is reabsorbed to the same degree, resulting in the concentration in the end of the proximal tubule being the same as in the beginning.