Question

Question
Ideal mobile phase pH for most silica based columns should lie
between.​

Answer 1

Answer:

It is important to note that, for maximum column lifetime, many silica based reversed-phase columns should be used within a limited pH range of approximately 2-8 and are therefore not suited to high pH work.

Answer 2

Answer:

Many silica based reversed-phase columns should be used within a limited pH range of approximately 2-8 and are therefore not suited to high pH work