Radioprotective efficacy of tender coconut water on electron beam irradiated swiss albino mice
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▶Lutein, a carotenoid compound, has previously been studied for its antioxidant and medicinal properties as well as the moderate protection it confers against gamma radiation.
▶ This study aimed at evaluating the effects of lutein against radiation-induced hematological and biochemical changes in mice
▶.The optimized dose of the compound was orally administered for 15 days, and the mice were irradiated (6 Gy) on day 15 after the administration of the compound. The groups were divided (6 mice in each group) into normal control, radiation control, gallic acid control, 10% DMSO control, lutein control, and irradiated groups pretreated with gallic acid, 10% DMSO, and lutein.
▶Gallic acid was used to maintain a standard since it is a proven radioprotector. Within 24 hours post irradiation, the animals were anesthetized and sacrificed. The hematological, biochemical, and antioxidant changes were determined using suitable methods.
▶Data were analyzed by the Kaplan-Meier curve (log-rank test) and ANOVA (the Tukey test). The independent t test was used to compare the independent groups. SPS
# Be bRainly
▶Lutein, a carotenoid compound, has previously been studied for its antioxidant and medicinal properties as well as the moderate protection it confers against gamma radiation.
▶ This study aimed at evaluating the effects of lutein against radiation-induced hematological and biochemical changes in mice
▶.The optimized dose of the compound was orally administered for 15 days, and the mice were irradiated (6 Gy) on day 15 after the administration of the compound. The groups were divided (6 mice in each group) into normal control, radiation control, gallic acid control, 10% DMSO control, lutein control, and irradiated groups pretreated with gallic acid, 10% DMSO, and lutein.
▶Gallic acid was used to maintain a standard since it is a proven radioprotector. Within 24 hours post irradiation, the animals were anesthetized and sacrificed. The hematological, biochemical, and antioxidant changes were determined using suitable methods.
▶Data were analyzed by the Kaplan-Meier curve (log-rank test) and ANOVA (the Tukey test). The independent t test was used to compare the independent groups. SPS
# Be bRainly
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