Reaction mechanism of alcohol with thionyl chloride
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Mechanism of the Reaction of Alcohols with Thionyl Chloride
First, a nucleophilic oxygen atom of the alcohol displaces a chloride ion from thionyl chloride to form a protonated alkyl chlorosulfite intermediate. Subsequent deprotonation of this intermediate by a base yields the alkyl chlorosulfite, an inorganic ester.
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Mechanism of the Reaction of Alcohols with Thionyl Chloride
First, a nucleophilic oxygen atom of the alcohol displaces a chloride ion from thionyl chloride to form a protonated alkyl chlorosulfite intermediate. Subsequent deprotonation of this intermediate by a base yields the alkyl chlorosulfite, an inorganic ester.
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