Reserpine induced hypothermia is an animal model for the assessment of
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Reserpine is a drug, primarily used in the treatment of hypertension.
Researchers use Reserpine administered in mice to produce a practical animal model for depression. This model has been used in numerous experiments to examine and compare the symptoms of depression in mice to those of humans, as well as determining the efficacy of certain anti-depressant medications.
Basically, reserpine-induced hypothermia is an animal model used in the screening of antidepressants.
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Antagonism of reserpine-induced hypothermia is an animal model used in the screening of antidepressants. The activity of imipramine on this test is partly impaired by propranolol.
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