Short chain fatty acid production by probiotic organisms in the gastrointestinal tract
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--- Although most of the SCFAs are absorbed in the colon, 10 to 20% are excreted in the feces ( 4 ). ... Lactic acid is another short chain fatty acid that is important to monitor. Bacteria in the GI tract that produce lactate include lactobacilli, bifidobacteria, enterococci, streptococci and Eubacterium (9). They are produced when the friendly gut bacteria ferment fiber in your colon, and are the main source of energy for the cells lining your colon. For this reason, they play an important role in colon health (1). Excess short-chain fatty acids are used for other functions in the body
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In the human gastrointestinal tract, the highest SCFA concentration is found in colon at a molar ratio of approximately 60:20:20 for acetate:propionate:butyrate (Table 1), taken from post mortem human subjects (42). Table 1. SCFAs concentration in human samples.SCFAs are produced when dietary fiber is fermented in the colon. Macronutrient composition (carbohydrate, protein, or fat) of diets affects circulating SCFAs. Acetate, propionate, and butyrate are the three most common SCFAs.
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