show a table showing the location, substrate acted upon, effects and products of enzymes
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The insecticidal activity of Bacillus thuringiensis (Bt) was discovered in 1901 in Japan, where the bacterium was isolated from infected silkworms, and was later (1911) rediscovered in Germany in infected flour moth chrysalids (reviewed in Sanchis, 2011). For over 50 years, Bt strains and their insecticidal proteins have been used as commercial biological review summarizes primarily what is known about food safety, however, as part of this review the mechanism of action, taxonomic specificity, and environmental safety of Bt proteins particularly Cry proteins has been included. The large amount of safety information that has been generated on both Bt microbial insecticides and GM crops that produce specific Bt proteins is discussed, and technical assessments of the small number of studies that have raised concerns
about the safety of Bt Cry proteins are provided. The many benefits of Bt crops beyond insect control p
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