Question

Show how you would use a Strecker synthesis to make isoleucine.

Answer 1

Explanation:

The Strecker Amino Acid Synthesis

The Strecker synthesis is a two-step procedure for the synthesis of amino acids. It begins with the addition of cyanide ion to an imine, forming an alpha-amino nitrile. This is then hydrolyzed (e.g. with strong acid) to give an alpha-amino acid. By varying the R group on the imine, a wide variety of amino acids may be made this way.

Answer 2

Explanation:

Strecker synthesis to make isoleucine.