Signaling pathways in chronic myelogenous leukemia
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Rho-signaling pathways in chronic myelogenous leukemia. ... The molecular cause of CML is the fusion oncoprotein Bcr-Abl whose constitutive tyrosine-kinase (TK) activity maintains enhanced signaling through multiple signal transductionpathways and confers proliferative and survival advantage to CML cells..........
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