Question

siskel sales anaemia shows

Answer 1

In sickle cell anaemia which is caused by the replacement of valine in place of glutamic acid(6th amino acid of DNA structure.), the red blood cells basically become sickle shaped that is, it resembles the shape of sickle. The oxygen carrying capacity of haemoglobin in such individuals is very low. In this condition, clumping and thereby destruction of erythrocytes occur more often. As a result blood vessels are obstructed and the circulatory system,brain , lungs,kidneys,etc are damaged.