Question

skeleetal muscle relaaxant which is depolarizing agents muscle cell have contractile protein which help in contraction and relaxation of the muscle give the mechanism by which nerve cell stimulate the contraction in...

Answer 1

In the resting state, the electrical potential of the inside of a nerve cell is negative with respect with the outside. When the action potential depolarizes the nerve terminal, an influx of calcium diffuse into the cell via channels. The entry of calcium facilitates the release of acetylcholine (ACh). These ACh molecules then diffuse across the synaptic cleft and bind to the nicotinic cholinergic receptors at the motor end-plate. This depolarizes the end-plate generating an action potential propagating the activation of sodium channels throughout the muscle fiber.