smallpox is caused by ? give answer in 200 to 300 words
Answers
Answer:
Smallpox is caused by infection with the variola virus. The virus can be transmitted: Directly from person to person. Direct transmission of the virus requires fairly prolonged face-to-face contact.
Explanation:
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A poxvirus called variola (Poxviridae family of viruses, genus Orthopoxvirus) causes smallpox. Variola is a relatively large brick-shaped virus that contains double-stranded DNA. The virus resides in large numbers in many organs (skin, kidneys, spleen, liver, and other organs) of infected people. Death occurs because of overwhelming toxemia, thought to be due to immune complexes trying to react to the large number of viral particles. Variola infection only occurs in humans, which was helpful in eradicating the disease. There are two strains called variola major and variola minor (also known as alastrim). As implied by the names, variola major is more likely to cause serious disease and death than variola minor.
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